As he is escaping, he comes across a Thermo-nuclear warhead. By setting his 'highly flammable Taliban cell-mate' on fire, he breaks out of his holding cell and escapes the base, leaving behind him a trail of dead soldiers who tried to stop him. Eventually, Postal Dude is arrested by the National Guard while escaping from the base, and is held prisoner at the Paradise Military Base Stockade. During this, the camp comes under attack by the National Guard. Ultimately, the terrorists at the camp begin shooting at him, and he must fight through them to find ordnance himself. Postal Dude comes up with the plan of using explosives to show this, and decides it will be a good idea to ask Al Qaeda at their Terrorist Training Camp for some ordnance. He also says that he needs a way to show the world that Running With Scissors is not to be messed with. Upon leaving, Vince Desi calls Dude again, and tells him that Mike J has became infected with the mad-cow disease, and has promoted Dude to marketing manager. Seeing it as 'perfectly legal', Postal Dude accepts the offer and kills all Elephants inside the preserve. As Postal Dude is leaving Vince's house, he is offered by a Mexican man outside an Elephant Preserve to kill all the Elephants inside with a Scythe so that their legs can be made into baskets for children. Using weapons from the armory in the basement, Vince, the RWS staff and Dude successfully fend off the zombie infestation. The next morning, Postal Dude wakes up to find that Vince's house has been infested with zombies. To celebrate, Vince invites Postal Dude to his house for a party with the Postal Babes. Following a boss battle, Postal Dude kills Haugslop and retrieves the golden disc. He fights through numerous security guards, and finds himself in Phraud Hogslop's office, the CEO of the company. Dude accepts, and goes to the company's headquarters. Following the cutscene, Postal Dude is called by his ex-boss Vince Desi, who asks him to go to Bullfish Interactive, the 'Rival Video Game Company', and retrieve a Gold Master. The player never actually gets to do this Pigeon Relocator mission, and instead, a cutscene plays showing the aftermath.

Impressed by his work, the man promotes Postal Dude to the 'Pigeon Relocator', and gives him a Rocket Launcher in order to do the job. Dude accepts, and kills all the diseased cows on a pasture with a sledgehammer and grenades, at the same time coming across Vegetarians who try and intervene. After killing off all the zombies, a man approaches Postal Dude and offers him the job of killing diseased cows to prevent the infection from further spreading.

As he is getting something to eat at an Asian restaurant, mad-cow infected zombies overrun the place, and he must assist in killing them all. After reading these letters, the Postal Dude eventually leaves the hospital after having major Gary Coleman hallucinations. After waking up from what appears to be a coma, the Postal Dude reads various 'get well' cards beside his bed, however they turn out to be threatening letters from a Dog Pound, land owner and his wife. In this expansion, it is revealed that The Dude survived the head-shot he received in the end of the main game (He shot himself to stop listening to The Bitch, his nagging wife) and is in Paradise's Hospital.

Postal 2 apocalypse weekend